Glutathione deficiency is a well documented condition in those with immune deficiency, cancer, MS and other chronic conditions. There's quite a bit of discussion about this in the AME archives as well.
The information I've found about supplementing, however, is confusing.
I have been using glutamine powder (a precursor to glutathione) supplementation intermittently for several years on the advice of an allopathic HIV specialist. Other references recommend another precursor, n-acetyl cycteine (NAC) for supplementation, which I've also been using the last two years. Acetyl l-carnitine (ALCAR) is yet another glutathione "booster" that is in my oversized list of supplements.
Needless to say, I'd like to reduce the quantities of supplements I'm taking.
Apparently taking glutathione itself orally is not very effective, due to low absorption rates in the digestive tract. There are some sublingual glutathione products available, but I'm not sure how they compare for dosing.
Does anyone have any additional information about the best supplement to counter glutathione deficiency? Are there other reasons to take NAC and carnitine besides glutathione deficiency?